Amazon TIC verification effective April 2024 — listings removed for non-compliance
COAs must be from production runs — pre-production testing not accepted
Heavy metals + microbial + adulterants required for high-risk supplement intents
cGMP certificates must be third-party accredited — first-party audits not accepted
Amazon TIC verification effective April 2024 — listings removed for non-compliance
COAs must be from production runs — pre-production testing not accepted
Heavy metals + microbial + adulterants required for high-risk supplement intents
cGMP certificates must be third-party accredited — first-party audits not accepted
Amazon Supplement Compliance

Stop losing sales to
compliance failures.

Amazon's TIC verification model has changed the rules. Qalitex helps supplement sellers on Amazon.com and Amazon.ca build a defensible evidence pack — before the delisting notice arrives.

6mo
COA freshness window
4+
Testing panels required
0
First-party audits accepted
Free Gap Assessment
Get a written compliance risk score + recommended testing panel for your SKU(s).
No spam. Confidential. Response within 1 business day.
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Amazon changed the rules.
Most sellers haven't caught up.

Since April 2024, Amazon requires third-party TIC verification — not just a document upload. Listings are removed if compliance isn't confirmed by the stated deadline.

01 / LISTING GATE

TIC verification is now mandatory

Dietary supplement listings in flagged categories must be verified through an Amazon-approved Testing, Inspection & Certification organization via the Manage Your Compliance workflow. COAs submitted directly by sellers are not accepted.

02 / EVIDENCE GATE

Testing panels are category-specific

For bodybuilding, sports, sexual enhancement, weight management, and joint health: Amazon explicitly requires heavy metals, microbial, adulterant testing (NSF/ANSI 173-2024), and label claim tolerances per 21 CFR 101.36.

03 / cGMP GATE

Private audits are rejected

Facility cGMP compliance must be certified by an accredited third party. First-party audits, consulting audits, and FDA inspection records are explicitly not accepted. Expired certificates are equally disqualifying.

04 / LABEL GATE

Labelling accuracy is enforced

Amazon issues removal notices for extract amounts deemed inaccurate or misleading under 21 CFR 101.36 — even for botanical extracts. Violations can trigger account deactivation warnings.

05 / CLAIMS GATE

Disease claims trigger restrictions

Products positioned with anxiety, depression, arthritis, pain, or similar terms are flagged. Amazon has stated it will not consider reinstatement until such claims are removed from the detail page and all images.

06 / CANADA GATE

Amazon.ca requires NPN/DIN licensing

If Amazon identifies your product as an NHP or drug product on Amazon.ca, the listing may be blocked unless you hold a valid Health Canada license. Unlicensed NHPs cannot legally be listed or sold.

End-to-end compliance,
not just a lab order.

Amazon supplement compliance fails when evidence is internally inconsistent — label vs COA vs lot traceability. We align every layer.

🔍

Compliance Gap Assessment

We review your label, COA, and cGMP certificate against Amazon's current requirements and assign a written risk score with a recommended testing panel and remediation roadmap.

Starting point
⚗️

Testing Panel Design & Lab Coordination

We design the right panel for your product form and intended use — metals, microbial, potency, pesticides, adulterants — and coordinate with ISO 17025-accredited labs using production-run sampling.

Core service
📋

COA Quality Review & Formatting

COAs are checked for lot linkage, ISO 17025 scope alignment, unit harmonization with label declarations, method references, and Amazon-required attributes. Corrected layouts provided where needed.

Submission readiness
🔗

Chain-of-Custody & Sampling SOP

We provide sampling SOPs, tamper-evident chain-of-custody forms, and shipping condition guidance to ensure your testing results are defensible from production floor to lab receipt.

Defensibility
🏭

cGMP Evidence Pack Compilation

We validate your third-party cGMP certificate, confirm it isn't expired, and map the audited facility to your active SKUs — creating a submission-ready evidence packet.

Gate 3 compliance
🇨🇦

Amazon.ca / NHP Alignment Review

For Canadian marketplace sellers, we review NPN/DIN licensing status, bilingual labelling requirements, priority allergen compliance, and Health Canada product facts table alignment.

Canada-specific
🛠️

CAPA & Remediation Support

When a test fails or Amazon issues a notice, we help investigate root cause, design a retesting strategy, draft CAPA documentation, and package a resubmission evidence pack.

Remediation
📅

Annual Compliance Portfolio Management

Annual renewal reminders, rolling COA library management, multi-SKU submission calendars, and ongoing claims/labelling monitoring to keep your entire portfolio in active status.

Ongoing retainer

Required panels by
product type and intent

Costs vary by matrix complexity and analyte count. Ranges below reflect typical market pricing from ISO 17025-accredited commercial labs.

Test Category Typical Turnaround Typical Cost Range Amazon Status
Heavy Metals
(As, Cd, Hg, Pb via ICP-MS)
5–10 business days ~US$80–$250 Explicit — Required
Microbial Indicators
(APC, yeast/mould, E. coli, coliforms)
2–6 business days ~US$60–$250 / panel Explicit — Required
Pathogens
(Salmonella, Staph — matrix dependent)
3–7 business days ~US$40–$150 each Risk-based
Adulterants Screen
(NSF/ANSI 173-2024 reference list)
7–15 business days ~US$250–$1,200+ Explicit — High-risk intents
Pesticide Multi-Residue
(botanical-heavy or component-flagged)
7–14 business days ~US$200–$800 Risk-based / component review
Potency / Label Claim
(active verification per 21 CFR 101.36)
5–15 business days ~US$130–$350 / analyte Explicit — Label tolerance
Identity Testing
(dietary ingredient verification)
3–10 business days ~US$80–$300 cGMP baseline
Stability / Shelf-life
(expiry date substantiation)
Weeks to months ~US$500–$5,000+ Best practice / Health Canada

Your compliance workflow,
step by step.

A typical compliance cycle from gap assessment to live listing runs 6–10 weeks depending on panel scope and whether remediation is needed.

01

Risk & Label Review

We screen your ingredient list, claims, and label declarations for high-risk intents (bodybuilding, weight management, sexual enhancement, joint health, sports nutrition), disease-adjacent language, and quantitative accuracy against 21 CFR 101.36.

⏱ 2–5 business days
02

cGMP Evidence Pack Compilation

We validate your facility's third-party cGMP certification, confirm accreditation body and expiry status, and map the audited facility to the SKU(s) in scope. Private, first-party, and consulting audits are flagged for replacement.

⏱ 3–7 business days
03

Sampling Plan & Chain-of-Custody Setup

We produce a sampling SOP specific to your product form and lot, provide tamper-evident chain-of-custody forms, and confirm shipping conditions (temperature, carrier, timeline) to ensure the COA is defensible for production-run origin.

⏱ 1–3 business days
04

Lab Testing Execution

Samples are sent to ISO 17025-accredited labs with scope covering the required methods and matrices. We coordinate results across metals, microbial, potency, and any required adulterant or pesticide panels simultaneously.

⏱ 7–15 business days (varies by panel)
05

COA Quality Check & Evidence Formatting

Every COA is checked for lot linkage, ISO 17025 scope match, unit alignment with label declarations, method references, and recency (six-month conservative standard). The full evidence pack is formatted for TIC submission.

⏱ 2–4 business days
06

TIC Verification & Submission

We support submission through the Manage Your Compliance workflow with the TIC provider, ensure all documentation is in acceptable format (PDF, complete product name, batch number, recency), and track confirmation status.

⏱ 3–7 business days (TIC-dependent)
Amazon.ca Requirements

Selling in Canada? NHP licensing is a hard gate.

Amazon.ca may identify your supplement as a Natural Health Product (NHP) or drug product, blocking the listing until you hold a valid Health Canada NPN or DIN. Qalitex reviews your product's NHP classification risk, licensing status, and labelling requirements before Amazon flags you.

🪪

NPN / DIN Licensing

All NHPs and drug products must be licensed by Health Canada. Listings of unlicensed products are prohibited on Amazon.ca.

🏷️

Bilingual Labelling & Product Facts Table

Canadian labels require bilingual text, lot number, expiry date, and compliance with the improved labelling framework including priority allergens.

⚠️

NHP Classification Risk Review

Products you believe are foods or cosmetics may be classified as NHPs by Health Canada. We flag classification risk before Amazon does.

Is your listing at risk?

⚠️ High-Risk Signals
  • 🔴 COA is older than 6 months or not tied to the current production lot
  • 🔴 Lab used for testing does not hold ISO/IEC 17025 accreditation for the relevant scope
  • 🔴 cGMP certificate is from a first-party audit, consulting firm, or has expired
  • 🔴 Product is intended for weight management, sports, or sexual enhancement with no adulterant screen
  • 🔴 Label includes terms like "anxiety," "depression," "pain relief," or "anti-inflammatory"
  • 🔴 Botanical extract declared on label without a verified potency COA linked to that lot
  • 🔴 Selling on Amazon.ca without confirmed NPN/DIN or without checking NHP classification status
✅ Compliance-Ready Signals
  • 🟢 COA from a current production lot, issued within 6 months, from an ISO 17025-accredited lab
  • 🟢 Lab's accreditation scope explicitly covers the test method, analyte, and matrix in question
  • 🟢 cGMP certificate issued by an accredited third-party auditor, current, and mapped to the producing facility
  • 🟢 Heavy metals, microbial, and adulterant panels completed for high-risk intent categories
  • 🟢 Potency/label claim COA results align with quantitative declarations on the Supplement Facts panel
  • 🟢 Claims limited to structure/function language with required FDA disclaimer; no disease positioning
  • 🟢 Amazon.ca products hold valid NPN/DIN and carry bilingual labels with lot number and expiry date

Choose your engagement model

All models include a compliance gap assessment. Final quotes are customized to your SKU count, product forms, and required testing scope.

Per-SKU Onboarding

Fixed Fee / per SKU
  • Label & claims review
  • Testing panel design
  • Evidence pack compilation
  • TIC submission coaching
  • COA quality check
Get a Quote

Portfolio Retainer

Monthly / multi-SKU
  • Annual renewal calendar
  • Rolling COA library
  • Multi-SKU submissions
  • Claims monitoring
  • Priority support
Get a Quote

Expedited Track

Add-On / any model
  • Rush lab coordination
  • Priority COA review
  • Same-week submission pack
  • Dedicated contact
  • Status updates daily
Add to Quote

Request a Supplement Compliance
Gap Assessment

Upload your label, COA, and cGMP certificate (if available) and receive a written panel recommendation, estimated cost/timeline, and submission checklist — aligned to the current TIC verification model.

About You


Your Amazon Situation


Current Documentation Status


Target Timeline

Your information is kept confidential. We do not share data with labs or TIC providers without your permission. Response within 1 business day.

Assessment Request Received

Thank you. A Qalitex compliance specialist will review your submission and respond with a written risk score, recommended testing panel, and timeline estimate within 1 business day.

Check your inbox — we'll send a confirmation with a document upload link so you can share your label, COA, and cGMP certificate ahead of your call.